TOKYO--22 Mar--PRNewswire-AsiaNet/ InfoQuest
- First Presentations of European-Australian and North American Phase III
Trials at European Association of Urology Congress Astellas Pharma Inc. (http://www.astellas.com/en/corporate/) (TSE:4503,"Astellas") today announced the results of two pivotal phase III clinical trials for mirabegron, the first of a new class of compounds under development for the treatment of overactive bladder (OAB), show mirabegron significantly improves key OAB symptoms - urinary incontinence and frequency of micturition.(1,2) These data were presented for the first time this week at the 26th annual congress of the European Association of Urology, in Vienna, Austria, 18-22 March 2011.
After 12 weeks treatment with once daily mirabegron, significant improvements from baseline were seen in the co-primary endpoints, incontinence episodes/24 hours and micturitions/24 hours, compared with placebo (p